Search on: KU AUTOANTIGEN 
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Descriptor English:   Ku Autoantigen 
Descriptor Spanish:   Autoantígeno Ku 
Descriptor Portuguese:   Autoantígeno Ku 
Synonyms English:   G22P1 Antigen
Ku Antigen
Ku Autoantigen, 70 kDa
Ku Autoantigen, 80 kDa
Ku Heterodimer
Ku Protein
Ku70 Antigen
Ku80 Antigen
X-ray Repair Cross-Complementing Protein 5
X-ray Repair Cross-Complementing Protein 6
XRCC5 Protein
XRCC6 Protein
Antigen, G22P1
Antigen, Ku
Antigen, Ku70
Antigen, Ku80
Autoantigen, Ku
Heterodimer, Ku
X ray Repair Cross Complementing Protein 5
X ray Repair Cross Complementing Protein 6  
Tree Number:   D08.811.277.040.025.159.155
D08.811.399.340.155
D12.776.260.525
D12.776.660.625.625
D23.050.290.625
Definition English:   An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION. 
History Note English:   2017 (1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56468 
Unique Identifier:   D000072200 

Occurrence in VHL: 		 

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